Growth Hormone Optimization

Growth Hormone Optimization

Peptides

IPAMORELIN


Ipamorelin is one of the latest and greatest peptides in the growth factor family. Deemed one of the safest GHRP's, Ipamorelin is a selective growth hormone (GH) Secretagogue and Ghrelin receptor agonist.

This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other peptides in its class. 

Gland Stimulated: Pituitary Gland

BENEFITS OF IPAMORELIN:

  • Decreased body fat
  • Increased collagen production
  • Increased lean muscle mass
  • Improved sleep
  • Increased cellular repair and & Regeneration
  • Increased IGF-1
  • Increases bone mineral content
  • Counteracts glucocorticoid catabolic effects
  • Less appetite stimulation than GHRP-6
  • Less release of cortisol, prolactin, and aldosterone

Ipamorelin has been shown to be highly potent and has also demonstrated good safety and tolerability in human clinical studies. 

Research has shown that Ipamorelin is growth hormone specific, which means that the pituitary hormones (such as cortisol are unaffected). 

Ipamorelin may be one of the best alternatives available to HGH therapy.

As an added perk, it does not promote increased production of the enzyme ghrelin, which stimulates hunger. This means that it will not make you hungry, due to Ipamorelin's ability to control points of gastric, appetite, and growth motility.

Another very significant positive difference is that Ipamorelin does not display a capacity to significantly boost levels of cortisol, which can affect the body in unwanted ways. Patients on other types of secretagogue therapies have reported jitters, cold sweats or nervousness because therapy’s overall impact on cortisol levels. 

IPAMORELIN FAQS

Does Ipamorelin make you hungry? 
No. Ipamorelin does not increase ghrelin levels and therefore will not make you hungry. While some growth hormone peptides increase the production of the enzyme ghrelin, which stimulates hunger, but Ipamorelin does not.

How much does Ipamorelin cost?
Our Ipamorelin comes as a prescription and prices range from $400-$600 for a 3-5 month treatment. Ipamorelin is administered as an injection usually 5 out of 7 days per week.
 
What is CJC/Ipamorelin? 
CJC and Ipamorelin work together to stimulate the pituitary for optimized growth hormone production. By combining CJC-1295 with Ipamorelin, more receptors are activated which leads to increased growth hormones output. This is the second best combination on the market, add IGF-1 to this and THAT is the best combination.  
 
Does Ipamorelin cause weight gain? 
No. Compared to GHRP-6 and GHRP-2, Ipamorelin does not raise negative hormones such as cortisol (responsible for stress and muscle loss), prolactin (responsible for sexual side effects and water retention) or ghrelin (responsible for hunger. It is used for those looking to gain muscle, lose fat and provide anti-aging benefits.

What's the difference between Sermorelin and Ipamorelin? 
Like sermorelin, ipamorelin helps stimulate natural growth hormone production. Ipamorelin is unique because it also stimulates the production of IGF-1 in the liver independent of GH levels. This means that ipamorelin has the ability to more potently stimulate systems related to growth and repair throughout the body.
 

MK-677


MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Therefore, we can expect that ibutamoren may also affect these functions. It increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

BENEFITS OF MK-677:

Helps Build Muscles: Ibutamoren is frequently used as an anabolic substance, to increase lean body mass. It is orally active and can be taken once a day. MK-677 stimulates Growth Hormone and IGF-1 which each factor in significantly to maintaining lean body mass. Growth Hormone is believed by many to stimulate an increase in muscle size and strength and the ability of MK-677 to increase Growth Hormone production make it a popular choice.

One study that studied 60-year-olds indicated that injections to stimulate Growth Hormones led to increased strength in thigh muscles. When it comes to MK-677 stimulating muscle growth, its results will vary by person depending on their exercise regimen and if they have any health conditions.

In another study of 24 obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR)

Reduces Muscle Wasting: MK-677 has shown in recent studies to alleviate muscle wasting that can be caused by a decline in protein within an individual’s diet. In one study a group of healthy young adults were tested to determine if MK-677 could reverse protein catabolism and the results proved to be quite positive. As a result, MK-677 is theorized to be possibly being an effective treatment for individuals who suffer from catabolic conditions.

Increases Bone Density: Several studies have indicated that long-term use of MK-677 can have tremendous results to increase bone mineral density. This finding can benefit several populations including obese individuals, older adults, and women with menopause. These distinct populations can have detrimental health problems due to low bone mineral density and MK-677 has proven to be an effective treatment for many of them.

In 24 healthy obese male volunteers, ibutamoren increased bone turnover.

In 187 elderly adults (65 years or older), ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover in multiple studies.

In one study with 292 post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.

The groups of people who serve to benefit by MK-677’s ability to increase bone density must research the possibility of any long-term side effects since increases in bone density typically take more than a year’s use. 

Improves Sleep: Since Growth Hormone is known to help improve sleep quality, it is commonly thought that Ibutamoren Mesylate can assist with sleep quality since it stimulates production in Growth Hormone.

A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration.

Apart from scientific studies, there have been many reports of subjective improvements in sleep quality.

Combats Aging and May Increase Longevity: As seen with other hormones in the body, Growth Hormone naturally begins a steady decline once a certain age is hit. Individuals who are aging can benefit from taking MK 677 since Growth Hormone and IGF-1 will be increased in the body among its consumption. Aging individuals who take MK 677 can improve their overall hormone profiles as they give their declining GH levels (Growth Hormone levels) a boost.  

In a study with 65 elderly men and women, daily ibutamoren increased GH and IGF-1 levels to those of healthy young adults without serious adverse effects.

In another study with 24 obese males, ibutamoren rejuvenated the growth hormone profile.

May Have Nootropic Effects: Since MK-677 shares a lot of similar qualities to Ghrelin and binds to its receptors, it is believed that MK 677 can have the same effects on the brain that Ghrelin has.

However, there are no studies that confirm whether or not MK 677 has direct nootropic effects on the brain. Scientists do have hope though that a couple of noticeable indirect methods may explain how MK 677 can be of assistance to cognitive function. Looking back at the previous section, one method that shows promise is Ibutamoren’s ability to improve sleep quality by increasing REM sleep. Obtaining the proper amount of sleep each night is extremely important when trying to achieve adequate cognitive function. MK-677 can improve cognitive function by assisting individuals with the ability to get a good night’s rest. The ability of MK-677 to stimulate IGF-1 production can also indirectly improve cognitive function based on IGF-1’s role in cognitive function. One study indicated that IGF-1 positively affected participants’ ability to perform well on cognitive tests. We know that sleep is essential for good cognitive function.

Beneficial in Treating Growth Hormone Deficiency: Ibutamoren can increase growth hormone, IGF-1, and IGFBP-3 levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations of prolactin, glucose, triiodothyronine (T3), thyroxine (T4), thyrotropin, cortisol or insulin.

In severely GH-deficient men, ibutamoren increased IGF-1 and growth hormone, with no significant changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose were increased.

Side effects:

Overall, MK 677 has not produced very many side effects for its users to be concerned about, but certain populations may have certain side effects to look out for. Individuals who are vulnerable to insulin sensitivity or who have Diabetes may be at risk when taking MK-677. Symptoms associated with these conditions could possibly be exacerbated by the use of MK 677. As with any other compound, correct dosing and usage of MK-677 is the key. In studies that looked at how MK-677 increases muscle mass, the dosage was key. Side effects of MK-677 are usually the result of a handful of two things: improper dosage and extended use.

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often which are:
  • Increased appetite
  • Lethargy
  • Joint pain if you have previous medical conditions or elevated hormone levels
  • Insulin resistance
  • Possible increase in prolactin levels, which can be controlled
But when dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly. The results from using MK-677 are evident in just a couple of days and with proper dosing and stacking, include:

Conclusion:

it has shown to provide numerous health benefits for individuals with certain conditions. Those with low bone density, have trouble sleeping at night, and with catabolic conditions can all benefit greatly from the use of MK 677. The ability of the MK 677 secretagogue to effectively secrete Growth Hormone and IGF-1 proves to be a useful tool for many different populations. MK 677 has shown through numerous studies to benefit the elderly, those with obesity, have problems sleeping, have low bone density, and others. For these populations, MK 677 can be used as a helpful tool to combat issues that can be caused in large part due to a lack of Growth Hormone and IGF-1.

SERMORELIN


WHAT IS SERMORELIN?
Sermorelin was first developed in the 1970's. It is a peptide which contains a total of 29 amino acids whose primary function is to encourage the pituitary gland to naturally produce more Human Growth Hormone (HGH). Sermorelin is often combined with other peptides like GHRP-2 and GHRP-6 which are growth hormone releasing peptides (also known as growth-releasing factor). This combination, when administered via daily injections, will encourage your pituitary gland to secrete HGH at a much higher rate.

SERMORELIN AND HGH
In order to fully understand how Sermorelin works, it is important to understand how HGH works and what the HGH benefits are. HGH is secreted by our pituitary glands every night while we sleep. The primary function of HGH is to help control the reproduction and growth of our cells and organs. As we age, our body's natural human growth hormone output decreases after peaking in our mid 20's. By the time we are in our 40's, our HGH levels diminish by 40% of what it was at age 20 and as we continue to age, those HGH levels continue to decrease dramatically. In order to regain those youthful HGH levels, your pituitary glands need to be stimulated to begin production of HGH again. This can be done with Sermorelin. Sermorelin alone or combined with GHRP-2 and GHRP-6 is a safe and effective way to stimulate and increase your body's human growth hormone (HGH) production. 

SERMORELIN THERAPY
In order to implement an effective, safe Sermorelin therapy program, Our physicians will determine the proper dosage of Sermorelin on a case-by-case basis. In order to determine the right amount amount of Sermorelin for you, they will evaluate your blood tests and medical history information. If you haven't had recent blood work, one of our physicians can order this to be done at a location that is convenient for you. Call 480-839-4131 to schedule your consultation with him where you can discuss your HGH therapy options in their entirety.

If it is determined that Sermorelin therapy will be safe and effective for you, you'll begin the therapy. Sermorelin therapy consists of daily injections of Sermorelin which stimulates the pituitary gland to produce increased natural secretion of human growth hormone or HGH.

The approved medical use for this prescription drug is to increase growth hormone levels in children who have growth hormone deficiency. The medical use of Sermorelin in adults with low levels of the human growth hormone is an unlabeled medical use of the drug to obtain the treatment benefits described on this page. Although not specifically approved for increasing growth hormone levels in adults, prescribing Sermorelin for adults who have growth hormone deficiency is legally permissible and within the discretion of the treating physician. Since Sermorelin acetate is approved as safe for use in children to increase their production of growth hormone, it is considered safe for use in increasing the natural production of growth hormone in adults deficient in growth hormone.

BENEFITS OF SERMORELIN
For a list of the benefits that come from healthy HGH levels, take a look at our HGH Benefits page. Common aging related issues such as low energy levels, low sex drive, poor stamina, increased fat levels, lack of skin elasticity, and poor mental function can be improved by Sermorelin and youthful HGH levels.

PEPTIDE THERAPY CONSULTATIONS

If you have additional questions about peptide therapy or if you would like to know more about these peptides give us a call or book your appointment now!
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